Ginkgo biloba extract is a fairly well-known dietary supplement traditionally used to enhance cognitive function. It is a potent antioxidant and has been shown to be neuroprotective in several studies. One of the ways in which Ginkgo works is by reducing platelet aggregation and thereby inhibiting clot formation. Ginkgo has also been shown to potentially improve memory, attenuate antidepressant-induced sexual dysfunction, and increase blood flow to extremities.
A recent study investigated the use of Ginkgolide B, a constituent of Ginkgo biloba, in preventing migraines with aura. A combination of Ginkgolide B, CoQ10, and riboflavin (vitamin B2) were given twice daily for six months. A significant decrease in both migraine frequency and migraine duration were found with treatment.
Ginkgo is traditionally used in doses of 50-400 mg per day. It would be difficult to estimate the amount needed to achieve a similar quantity of Ginkgolide B as used in the study, but anywhere between 200 - 400 mg would be a reasonable guess.
Ginkgo is available over the counter and is generally considered to be quite safe, though it should not be taken before surgery or in combination with other anticoagulants. For those suffering recurrent migraines, Ginkgo may well be worth a try.
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